We did it! Yay! Congratulations to us!
After what seemed to be the longest revision ever, our mouse kidney multi-omic characterization is published in Nature Genetics! Congrats to Siqi (former PostDoc), Simon and Ruiyang (former grad student) for this achievement.
We are pleased to see that our recent germline CPTAC Cell paper is getting noticed across the globe! Here are some of the news and reports on our paper.
Mount Sinai press release: https://www.mountsinai.org/about/newsroom/2025/study-reveals-how-inherited-genes-help-shape-the-course-of-cancer
Siteman: https://siteman.wustl.edu/how-do-inherited-cancer-mutations-drive-tumor-growth/
Eduard and Kathleen's press release (Spain): https://www.carrerasresearch.org/en/news/new-proteogenomic-research-links-germline-variants-to-cancer-progression
ASCO post: https://ascopost.com/news/april-2025/germline-variants-may-impact-unique-nature-of-patients-cancer/
Others :
https://scitechdaily.com/born-with-it-how-your-dna-shapes-cancer-before-it-even-starts/
https://www.newswise.com/articles/study-reveals-how-inherited-genes-help-shape-the-course-of-cancer
https://www.bioworld.com/articles/719433-germline-variants-impact-on-pan-cancer-proteome?v=preview
Our group published a proteogenomic germline study in Cell in collaboration with CPTAC consortium. Congratulations to Fernanda Martins Rodrigues and other co-authors for this tremendous effort! WashU has also published a report about this publication. Read it here.
On February 28th, Julia successfully defended her PhD! Congratulations! We are excited to see what other projects await you in the future.
EJ gave a wonderful presentation on our progress at the GDAN meeting in Houston, Texas.
On December 9th, Wagma earned her Doctorate Degree in Chemistry. The first Chemistry department student from our lab! She focused on investigating the functional role of ccRCC markers associated with cancer progression. Congrats Dr. Caravan!
Our first Biomedical Engineering student got his PhD on November 21st with his thesis focusing on Spatial insights in tumor biology. Huge congrats!
Read it here.
Our Nature paper “Tumour evolution and microenvironment interactions in 2D and 3D space” published last week was featured in a Nature research briefing by W. Kimryn Rathmell, M.D., Ph.D., director of NIH’s National Cancer Institute (NCI), and Dinah Singer, Ph.D., NCI deputy director for scientific strategy and development. Enjoy it here.