Welcome our new open access Nature Genetics paper. Dr. Cui Zhou, Dr. Jayasinghe, Dr. Chen and others analyzed spatial heterogeneity of driver events in PDAC, traced transitional cell populations and identified microenvironment cooperation in untreated and chemo-resistant pancreatic cancer. Talented artist Jessica Johnson created a stunning candidate cover image. Too bad it was not selected! WashU news also talked about this high impact paper.