This image depicts how aberrant DNA methylation patterns—represented by the rocks being held by the mischievous children—upset the balance of epigenetic marks in the cell’s DNA, creating a permissive landscape for tumor progression. The ER's ribosomes and Golgi apparatus in the backdrop represent concurrent transcriptional and translational shifts coming from the seesaw's tilt. The emotional response of the kids on the seesaw mirrors the profound impact these epigenetic changes can have on our cells. Designed by Stephish Liu.